Process for the preparation of estetrol: United States Patent
The invention relates to a process for obtaining Estetrol or a salt or solvate thereof, the process comprising: a) reacting a compound of formula (IV) or a salt or solvate thereof, wherein R.sup.1 is a hydroxyl protecting group selected from a silyl ether, an ether, an ester, a carbamate and a carbonate, and R.sup.2 is a hydroxyl protecting group selected from an ether, with an oxidizing agent selected from OsO.sub.4 or a source of osmium tetroxide to produce Estetrol or a compound of formula (II) or a salt or solvate thereof wherein R.sup.1 is as defined previously; and b) if a compound of formula (II) is obtained in step a), deprotecting said compound to produce Estetrol. ##STR00001##
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yazar | Juan Jose Ferreiro Gil |
---|---|
Tarafından yayınlandı | 3 Aralık 2020 |
Flower Love Press 15 x 0,7 x 22 cm 15 x 0,4 x 22 cm 15 x 0,5 x 22 cm 15 x 0,3 x 22 cm 28 Şubat 2018 Dazzle Book Press U.S. Department of the Interior 15 x 0,6 x 22 cm 21,6 x 0,6 x 27,9 cm 3 Aralık 2020 1 Ocak 2018 1 Ocak 2016 Kolektif BrownTrout Publisher Collectif 1 Haziran 2018 30 Eylül 2020
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Sürüm ayrıntıları
yazar | Juan Jose Ferreiro Gil |
---|---|
isbn 13 | 979-8575004820 |
Yayımcı | Independently published |
DE OLDUĞU GİBİ | B08PJK76DR |
Tarafından yayınlandı Process for the preparation of estetrol: United States Patent | 3 Aralık 2020 |
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