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Oxidative Stress: Mechanisms and Disease Pathogenesis

Oxidative stress is an imbalance in the production of free radicals and the body’s inability to counteract their harmful effects or detoxify. This imbalance can cause disruptions in cellular signaling. Oxidative stress implies an increased production of oxidizing species and decrease in the effectiveness of antioxidant defenses. Moderate oxidation can trigger apoptosis, while more severe cases cause necrosis. Oxidative stress is considered to be an important element in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease, Huntington's disease, Lou Gehrig's disease, multiple sclerosis, autism, etc. Oxidative stress has been implicated in the incidence of cardiovascular diseases, as oxidation of LDL is a precursor to plaque formation. This book elucidates the concepts and innovative models around prospective developments with respect to oxidative stress. It unravels the recent studies in the mechanisms and disease pathogenesis of oxidative stress. Coherent flow of topics, student-friendly language and extensive use of examples make this book an invaluable source of knowledge.


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18,9 x 0,3 x 24,6 cm 18,9 x 0,6 x 24,6 cm 18,9 x 0,4 x 24,6 cm 15 Eylül 2020 3 Ocak 2017 WADE H MCCREE 28 Şubat 2018 30 Ekim 2011 Kolektif 28 Ekim 2011 Additional Contributors 18,9 x 0,2 x 24,6 cm 18,9 x 0,5 x 24,6 cm Mdpi AG ROBERT H BORK 15 x 0,5 x 22 cm 1 Ocak 2017 ERWIN N GRISWOLD
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Sürüm ayrıntıları
yazar Hayle Medical
isbn 10 1632418584
isbn 13 978-1632418586
Yayımcı Hayle Medical
Boyutlar ve boyutlar 21.59 x 1.27 x 27.99 cm
Tarafından yayınlandı Oxidative Stress: Mechanisms and Disease Pathogenesis 15 Eylül 2020

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