Matrix Metalloproteinase
Zinc-dependent matrix metalloproteinases (MMPs) belong to metzincins that comprise not only 23 human MMPs but also other metalloproteinases, such as 21 human ADAMs (a disintegrin and metalloproteinase domain) and 19 secreted ADAMTSs (a disintegrin and metalloproteinase thrombospondin domain). The many setbacks from the clinical trials of broad-spectrum MMP inhibitors for cancer indications in the late 1990s emphasized the extreme complexity of the participation of these proteolytic enzymes in biology. This editorial mini-review summarizes the Special Issue, which includes four review articles and 10 original articles that highlight the versatile roles of MMPs, ADAMs, and ADAMTSs, in normal physiology as well as in neoplastic and destructive processes in tissue. In addition, we briefly discuss the unambiguous involvement of MMPs in wound healing.
yazar | Mdpi AG |
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Boyutlar ve boyutlar | 16.99 x 2.24 x 24.41 cm |
Tarafından yayınlandı | 31 Ağustos 2020 |
18,9 x 0,6 x 24,6 cm Mdpi AG Kolektif ROBERT H BORK 18,9 x 0,4 x 24,6 cm 18,9 x 0,2 x 24,6 cm Additional Contributors 31 Ağustos 2020 3 Ocak 2017 28 Ekim 2011 18,9 x 0,5 x 24,6 cm 15 x 0,5 x 22 cm ERWIN N GRISWOLD 18,9 x 0,3 x 24,6 cm WADE H MCCREE 1 Ocak 2017 30 Ekim 2011 28 Şubat 2018
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Sürüm ayrıntıları
yazar | Mdpi AG |
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isbn 10 | 3039366483 |
isbn 13 | 978-3039366484 |
Yayımcı | Mdpi AG |
Boyutlar ve boyutlar | 16.99 x 2.24 x 24.41 cm |
Tarafından yayınlandı Matrix Metalloproteinase | 31 Ağustos 2020 |