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Ganglioside Biochemistry

This book presents the latest knowledge and the most recent research results in the field of ganglioside biochemistry.  The early chapters cover all relevant background on sialic acids and their biosynthesis, on N-glycolylneuraminic acid (Neu5Gc), which cannot be synthesized by humans, and on general aspects of ganglioside research.  Ganglioside adsorption, disorders of ganglioside degradation, and the regulation of gangliosides are thoroughly discussed. A major focus of the book is the role of gangliosides in cancer. Here, the discussion encompasses, for example, the biological importance, antigenicity, and immunological actions of tumor-associated gangliosides (TAGs), the significance of different glycolipids and gangliosides as TAGs, and emerging anti-cancer vaccine strategies. The ability of sialic acids and TAGs of tumor cells to escape immunosurveillance and immunoediting also receives detailed attention. The significance of sialic acids in regulation of the complement system is explained, and the closing chapter focuses especially on the role of sialyl T antigen in cancer.  The book will be of value for all who are interested in functional glycobiology and glycomic studies.


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1 Ocak 2017 18,9 x 0,5 x 24,6 cm 15 x 0,5 x 22 cm 28 Şubat 2018 30 Ekim 2011 18,9 x 0,6 x 24,6 cm WADE H MCCREE 29 Ekim 2011 Kolektif ERWIN N GRISWOLD ROBERT H BORK 3 Ocak 2017 28 Ekim 2011 Additional Contributors Mdpi AG 18,9 x 0,2 x 24,6 cm 18,9 x 0,4 x 24,6 cm 18,9 x 0,3 x 24,6 cm
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Sürüm ayrıntıları
yazar Cheorl-Ho Kim
isbn 10 9811558140
isbn 13 978-9811558146
Yayımcı Springer; 1st ed. 2020. baskı
Dilim İngilizce
Boyutlar ve boyutlar 15,5 x 23,5 cm
Tarafından yayınlandı Ganglioside Biochemistry 30 Ağustos 2020

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