Adiponectin : Implications in Health and Diseases: Adiponectin okumak kayıt olmadan

Adiponectin : Implications in Health and Diseases: Adiponectin

İş ve Ekonomi

Adiponectin is the name originated from its distinctive molecular characteristics (“adipo” + “nectin” = “adiponectin”) as it is a product of novel gene apM1 which is specific to adipocytes and uniquely possess a collagen-like domain with a nectin-like adherent property. Adiponectin is the most abundant peptide secreted by adipocytes, whose altered levels play a central role in obesity-related diseases, including insulin resistance/type 2 diabetes and cardiovascular disease. It is known to exert anti-diabetic and anti-atherosclerotic effects via adiponectin receptors (Adipors); AdipoR1 and AdipoR2. Adiponectin has direct actions in liver, skeletal muscle and the vasculature. Adiponectin administration in humans and rodents has insulin-sensitizing, anti-atherogenic, and anti-inflammatory effects and in certain settings, also decreases body weight. Therefore, adiponectin replacement therapy in humans may suggest potential versatile therapeutic targets in the treatment of obesity, insulin resistance/type 2 diabetes, cardiovascular disease and atherosclerosis.

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15,2 x 0,6 x 22,9 cm 31 Ağustos 2012 Gerardus Blokdyk 25 Mayıs 2010 20,3 x 0,3 x 26 cm N&S Collection 21,6 x 0,6 x 27,9 cm Aeryn Cartwright Icon Group International 28 Şubat 2018 20,3 x 0,2 x 26 cm 29 Ağustos 2009 20,3 x 0,4 x 26 cm 1 Ocak 2013 20,3 x 0,5 x 26 cm NAN RIEWALDT Kolektif 3 Haziran 2009

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